Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 3/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141413 | 0.83 | FFAR1 (0.52) | FFAR1SCDDGAT1USP30F2 | |
| SCHEMBL6644376 | 0.81 | LIPG (0.40) | LIPGLPLP4HBDGAT1USP30 | |
| SCHEMBL29071418 | 0.79 | FFAR1 (0.49) | FFAR1LIPGLPLP4HBDGAT1 | |
| SCHEMBL5853306 | 0.78 | LIPE (0.33) | LIPGLPLP4HBLIPE | |
| SCHEMBL680013 | 0.77 | FFAR1 (0.52) | FFAR1LIPGLPLP4HBDGAT1 | |
| SCHEMBL1650157 | 0.76 | FFAR1 (0.50) | FFAR1LIPGLPLDGAT1USP30 | |
| SCHEMBL19341509 | 0.75 | FFAR1 (0.44) | FFAR1SCDDGAT1USP30 | |
| SCHEMBL25826104 | 0.75 | FFAR1 (0.44) | FFAR1SCDDGAT1USP30 | |
| SCHEMBL860835 | 0.75 | FFAR1 (0.46) | FFAR1P4HBDGAT1USP30IRAK4 | |
| SCHEMBL22960902 | 0.75 | FFAR1 (0.47) | FFAR1LIPGLPLSCDDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |