Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22962251 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22778647 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962072 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962144 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22962335 | 1.00 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL22778689 | 0.98 | GNAI3 (0.46) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL23490184 | 0.91 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL20621280 | 0.91 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779350 | 0.91 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779490 | 0.91 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | GNAI3 572/4885GNAO1 897/4885GNAI1 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.