Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577937 | 1.00 | KIF18A (0.63) | KIF18A | |
| SCHEMBL22963049 | 0.90 | KIF18A (0.71) | KIF18A | |
| SCHEMBL29577909 | 0.90 | KIF18A (0.71) | KIF18A | |
| SCHEMBL22963044 | 0.86 | KIF18A (0.62) | KIF18A | |
| SCHEMBL22963043 | 0.84 | KIF18A (0.61) | KIF18A | |
| SCHEMBL29579172 | 0.84 | KIF18A (0.61) | KIF18A | |
| SCHEMBL30115247 | 0.81 | KIF18A (0.63) | KIF18A | |
| SCHEMBL29578175 | 0.80 | KIF18A (0.70) | KIF18A | |
| SCHEMBL22963107 | 0.80 | KIF18A (0.70) | KIF18A | |
| SCHEMBL22963106 | 0.79 | KIF18A (0.71) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026100-A1 | PYRIDINE DERIVATIVES AS KIF18A INHIBITORS | AMGEN INC. (US) | 2021-02-11 | — | — | WO | disclosed |