Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 6/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21303047 | 1.00 | KCNK2 (0.40) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL28706193 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL29440462 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL28706192 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL21272682 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL21272680 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL21272686 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL29467081 | 0.87 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1ACACB | |
| SCHEMBL18595922 | 0.79 | CASR (0.38) | KCNA5KCNH2KCNB1CASRMEN1 | |
| SCHEMBL29005622 | 0.78 | MEN1 (0.34) | KCNK2KCNA5KCNH2KCNB1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4241843-A2 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. Lundbeck A/S (DK) | 2023-09-13 | — | — | EP | disclosed |
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |