Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21272686 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL29467081 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL21272680 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL28706193 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL21272682 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL29440462 | 1.00 | KCNK2 (0.39) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL29005622 | 0.90 | MEN1 (0.34) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL21303047 | 0.87 | KCNK2 (0.40) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL22965249 | 0.87 | KCNK2 (0.40) | KCNK2KCNA5KCNH2KCNB1KMT2A | |
| SCHEMBL2714987 | 0.87 | DUT (0.41) | KMT2APOLBLMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |