Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952639 | 1.00 | KMT2A (0.39) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL28711056 | 0.98 | KMT2A (0.38) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL29440455 | 0.98 | KMT2A (0.38) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL28711055 | 0.98 | KMT2A (0.38) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| SCHEMBL22952665 | 0.86 | KMT2A (0.40) | KMT2ASMN1; SMN2L3MBTL1DRD1RXRA | |
| SCHEMBL22952800 | 0.84 | KMT2A (0.39) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL28719410 | 0.84 | KMT2A (0.39) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL29440435 | 0.84 | KMT2A (0.39) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| Hydrochloric Acid SCHEMBL28719412 | 0.84 | KMT2A (0.39) | KMT2ASMN1; SMN2L3MBTL1KCNK2KCNA5 | |
| SCHEMBL21288062 | 0.83 | CETP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |