Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29440435 | 0.98 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1TAS2R14KCNJ5 | |
| Hydrochloric Acid SCHEMBL28719412 | 0.98 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1TAS2R14KCNJ5 | |
| Hydrochloric Acid SCHEMBL28719410 | 0.98 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1TAS2R14KCNJ5 | |
| SCHEMBL22952639 | 0.86 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1KCNJ5KCNJ3 | |
| SCHEMBL22965294 | 0.86 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1KCNJ5KCNJ3 | |
| SCHEMBL22952800 | 0.86 | KMT2A (0.39) | KMT2ASMN1; SMN2DRD1TAS2R14KCNJ5 | |
| SCHEMBL22952702 | 0.85 | KMT2A (0.40) | KMT2ASMN1; SMN2DRD1TAS2R14KCNJ5 | |
| Hydrochloric Acid SCHEMBL28711056 | 0.84 | KMT2A (0.38) | KMT2ASMN1; SMN2DRD1KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL29440455 | 0.84 | KMT2A (0.38) | KMT2ASMN1; SMN2DRD1KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL28711055 | 0.84 | KMT2A (0.38) | KMT2ASMN1; SMN2DRD1KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548849-B2 | Alcohol derivatives as KV7 potassium channel openers | H. LUNDBECK A/S (DK) | 2023-01-10 | — | — | US | disclosed |
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |
| US-20210032196-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548849-B2 | Alcohol derivatives as KV7 potassium channel openers | KCNA7, KCNK17, KCNAB1 | KMT2A 854/4885SMN1; SMN2 3139/4885DRD1 1199/4885 |
| US-20210032196-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | KCNA7, KCNK17, KCNQ1 | KMT2A 656/4885SMN1; SMN2 2979/4885DRD1 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.