Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953366 | 1.00 | SCN4A (0.41) | SCN4ATRPM8KCNA5KCNH2CETP | |
| Hydrochloric Acid SCHEMBL28702855 | 0.98 | SCN4A (0.40) | SCN4ATRPM8KCNA5KCNH2CETP | |
| Hydrochloric Acid SCHEMBL28702853 | 0.98 | SCN4A (0.40) | SCN4ATRPM8KCNA5KCNH2CETP | |
| SCHEMBL22965315 | 0.88 | SCN4A (0.39) | SCN4ATRPM8TACR1CACNA1FCACNA1D | |
| SCHEMBL22952697 | 0.88 | SCN4A (0.39) | SCN4ATRPM8TACR1CACNA1FCACNA1D | |
| Hydrochloric Acid SCHEMBL28716051 | 0.87 | SCN4A (0.38) | SCN4ATRPM8TACR1CACNA1FCACNA1D | |
| Hydrochloric Acid SCHEMBL28716054 | 0.87 | SCN4A (0.38) | SCN4ATRPM8TACR1CACNA1FCACNA1D | |
| Hydrochloric Acid SCHEMBL29440473 | 0.87 | SCN4A (0.38) | SCN4ATRPM8TACR1CACNA1FCACNA1D | |
| SCHEMBL21272606 | 0.86 | GNRHR (0.41) | SCN4ATRPM8TACR1SLC6A2 | |
| SCHEMBL21272608 | 0.86 | GNRHR (0.41) | SCN4ATRPM8TACR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |