SCHEMBL2296586

SCHEMBL2296586

Fc1c(F)c(F)c(Nc2ccccn2)c(F)c1F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MAPK10 P53779 1/20 0.57
GFER P55789 1/20 0.57
RAB9A P51151 6/20 0.46
NPC1 O15118 4/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MITF O75030 1/20 0.46
MAPT P10636 1/20 0.46
ADRA2A P08913 2/20 0.44
ADRA2B P18089 2/20 0.44
ADRA2C P18825 2/20 0.44
PKM P14618 1/20 0.44
KDR P35968 3/20 0.43
CXCR4 P61073 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981869 0.82 KMT2A (0.55) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL29391624 0.79 KMT2A (0.76) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL221242 0.79 KMT2A (0.76) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL22909163 0.77 TSHR (0.49) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL29671325 0.77 TSHR (0.49) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL6574416 0.77 KMT2A (0.73) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL11133606 0.77 KMT2A (0.73) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL30947359 0.77 KMT2A (0.73) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL4243882 0.77 KMT2A (0.73) MEN1KMT2AMAPK10GFERRAB9A
SCHEMBL6175584 0.77 KMT2A (0.73) MEN1KMT2AMAPK10GFERRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500569-B2 COMPLEX; EMISSION OF BLUE LIGHT QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-12-31 US claimed
US-20020028351-A1 Luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-03-07 US claimed
US-6312835-B1 ALUMINUM AND BORON COMPLEXES OF 7-AZAINDOLES AND ALUMINUM COMPLEXES OF DI-2-PYRIDYLAMINES AND N-PHENYL-2-PYRIDYLAMINES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-11-06 US claimed
WO-1998036035-A1 LUMINESCENT COMPOUNDS AND METHODS OF MAKING AND USING SAME QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-08-20 WO claimed
US-7989089-B2 2-(9-anthryl)imidazo[4,5-f]-[1,10]phenanthroline (2) or 2-(2-pyridyl)imidazo[4,5-f]-[1,10]phenanthroline (4) LG DISPLAY CO., LTD. (KR) 2011-08-02 US disclosed
US-20040265629-A1 Organic luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-12-30 US disclosed
US-20040265628-A1 Organic luminescent compounds and methods of making and using same LG DISPLAY CO., LTD. (KP) 2004-12-30 US disclosed
US-6500569-B2 COMPLEX; EMISSION OF BLUE LIGHT QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-12-31 US disclosed
US-20020028351-A1 Luminescent compounds and methods of making and using same QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-03-07 US disclosed
US-6312835-B1 ALUMINUM AND BORON COMPLEXES OF 7-AZAINDOLES AND ALUMINUM COMPLEXES OF DI-2-PYRIDYLAMINES AND N-PHENYL-2-PYRIDYLAMINES QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-11-06 US disclosed
WO-1998036035-A1 LUMINESCENT COMPOUNDS AND METHODS OF MAKING AND USING SAME QUEEN'S UNIVERSITY AT KINGSTON (CA) 1998-08-20 WO disclosed