Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296586 | 0.82 | MEN1 (0.57) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL7341519 | 0.80 | MAPK10 (0.73) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL29796528 | 0.80 | MAPK10 (0.73) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL7978852 | 0.79 | KMT2A (0.66) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL221242 | 0.78 | KMT2A (0.76) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL29391624 | 0.78 | KMT2A (0.76) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL12682988 | 0.75 | MEN1 (0.46) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL11133606 | 0.75 | KMT2A (0.73) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL6574416 | 0.75 | KMT2A (0.73) | KMT2AMAPK10MEN1GFERRAB9A | |
| SCHEMBL30947359 | 0.75 | KMT2A (0.73) | KMT2AMAPK10MEN1GFERRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |