Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 10/20 | 0.59 |
| ▸ | FOLR1 | P15328 | 2/20 | 0.59 |
| ▸ | SLC19A1 | P41440 | 2/20 | 0.59 |
| ▸ | SLC46A1 | Q96NT5 | 2/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.59 |
| ▸ | GART | P22102 | 1/20 | 0.59 |
| ▸ | ATIC | P31939 | 1/20 | 0.59 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.59 |
| ▸ | FRK | P42685 | 1/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12238856 | 0.87 | TYMS (0.57) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL29094260 | 0.86 | TYMS (0.50) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL2260428 | 0.86 | TYMS (0.69) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL2260030 | 0.85 | TYMS (0.67) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL18755599 | 0.85 | TYMS (0.55) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL17652074 | 0.84 | TYMS (0.48) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL24845712 | 0.84 | TYMS (0.56) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL18551642 | 0.84 | TYMS (0.64) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL30130170 | 0.84 | TYMS (0.66) | TYMSFOLR1SLC19A1SLC46A1DHFR | |
| SCHEMBL24845716 | 0.84 | PNP (0.57) | TYMSFOLR1SLC19A1SLC46A1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026310-A1 | PROCESSES OF PREPARING POLYGLUTAMATED ANTIFOLATES AND USES OF THEIR COMPOSITIONS | L.E.A.F. HOLDINGS GROUP LLC (US) | 2021-02-11 | — | — | WO | disclosed |