Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 8/20 | 0.33 |
| ▸ | DPP4 | P27487 | 7/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25445845 | 0.84 | DPP4 (0.30) | DPP4 | |
| SCHEMBL25504815 | 0.83 | DPP4 (0.34) | DPP4DPP8DPP9 | |
| SCHEMBL25066412 | 0.83 | KRAS (0.32) | KRASDPP4DPP8DPP9 | |
| SCHEMBL25066395 | 0.83 | KRAS (0.32) | KRASDPP4DPP8DPP9 | |
| SCHEMBL25066398 | 0.81 | KRAS (0.34) | KRAS | |
| SCHEMBL25066396 | 0.81 | DPP4 (0.31) | DPP4 | |
| SCHEMBL25445847 | 0.79 | DPP4 (0.32) | DPP4 | |
| SCHEMBL25446275 | 0.78 | — | — | |
| SCHEMBL22431479 | 0.76 | JAK3 (0.39) | DPP4 | |
| SCHEMBL30501880 | 0.76 | SRC (0.40) | KRASDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040089-A1 | KRAS MUTANT PROTEIN INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040089-A1 | KRAS MUTANT PROTEIN INHIBITORS | KRAS, NRAS, APC | KRAS 1/4885DPP4 3172/4885SOS1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.