Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | RORA | P35398 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 4/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21449279 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL22968477 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL29139128 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL17971198 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL17394793 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL255026 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL16574736 | 0.92 | NPC1L1 (0.54) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL8383238 | 0.91 | NPC1L1 (0.53) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL20995445 | 0.91 | NPC1L1 (0.62) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL735215 | 0.91 | NPC1L1 (0.62) | NPC1L1SHBGRORAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021025973-A1 | HUMAN AMINOSTEROL ENT-03 COMPOUNDS, RELATED COMPOSITIONS COMPRISING THE SAME, AND METHODS OF USING THE SAME | ENTERIN, INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2021025974-A1 | HUMAN SQUALAMINE DERIVATIVES, RELATED COMPOSITIONS COMPRISING THE SAME, AND METHODS OF USING THE SAME | ENTERIN, INC. (US) | 2021-02-11 | — | — | WO | disclosed |