Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | RORA | P35398 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 4/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21449279 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL22968486 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL22968477 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL29139128 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL17971198 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL17394793 | 1.00 | NPC1L1 (0.55) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL16574736 | 0.92 | NPC1L1 (0.54) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL8383238 | 0.91 | NPC1L1 (0.53) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL20995445 | 0.91 | NPC1L1 (0.62) | NPC1L1SHBGRORAMEN1USP2 | |
| SCHEMBL735215 | 0.91 | NPC1L1 (0.62) | NPC1L1SHBGRORAMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025123045-A1 | PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-06-12 | — | — | WO | claimed |
| WO-2024168236-A2 | METHODS FOR DETECTING AND TREATING CAVERNOUS ANGIOMA | THE UNIVERSITY OF CHICAGO (US) | 2024-08-15 | — | — | WO | claimed |
| CN-112136043-B | Mass spectrometry method for detecting and quantifying liver function metabolites | 梅塔博隆股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117405870-B | Construction of predictive model of unstable plaque phenotype of coronary heart disease patient based on serum lipid metabolite | 北京市心肺血管疾病研究所 | 2024-03-19 | — | — | CN | claimed |
| EP-3321686-B1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON INC (US) | 2024-03-13 | — | — | EP | claimed |
| CN-117405870-A | Construction of predictive model of unstable plaque phenotype of coronary heart disease patient based on serum lipid metabolite | 北京市心肺血管疾病研究所 | 2024-01-16 | — | — | CN | claimed |
| US-20230375534-A1 | MEANS AND METHODS TO DIAGNOSE GUT FLORA DYSBIOSIS AND INFLAMMATION | VIB VZW (BE) | 2023-11-23 | — | — | US | claimed |
| US-11536726-B2 | Mass spectrometry assay method for detection and quantitation of liver function metabolites | METABOLON, INC. (US) | 2022-12-27 | — | — | US | claimed |
| US-11536730-B2 | Methods for diagnosing motor neuron diseases | SWANSEA UNIVERSITY (GB) | 2022-12-27 | — | — | US | claimed |
| US-20190310269-A1 | SYSTEMS AND METHODS FOR MEASURING OBESITY USING METABOLOME ANALYSIS | HUMAN LONGEVITY, INC. | 2019-10-10 | — | — | US | claimed |
| EP-2951313-A1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2015-12-09 | — | — | EP | claimed |
| US-20150285805-A1 | BIOMARKERS OF MULTIPLE MYELOMA DEVELOPMENT AND PROGRESSION | OSPEDALE SAN RAFFAELE SRL (IT) | 2015-10-08 | — | — | US | claimed |
| EP-2914962-A1 | BIOMARKERS OF MULTIPLE MYELOMA DEVELOPMENT AND PROGRESSION | Ospedale San Raffaele S.r.l. (IT) | 2015-09-09 | — | — | EP | claimed |
| WO-2014120449-A1 | BIOMARKERS RELATED TO INSULIN RESISTANCE PROGRESSION AND METHODS USING THE SAME | METABOLON, INC. (US) | 2014-08-07 | — | — | WO | claimed |
| US-20140221236-A1 | METABOLOMIC MARKERS FOR PRETERM BIRTH | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2014-08-07 | — | — | US | claimed |
| WO-2014068144-A1 | BIOMARKERS OF MULTIPLE MYELOMA DEVELOPMENT AND PROGRESSION | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2014-05-08 | — | — | WO | claimed |
| US-8679457-B2 | Metabolite biomarkers to distinguish Crohn's disease from ulcerative colitis and methods using the same | METABOLON, INC. (US) | 2014-03-25 | — | — | US | claimed |
| US-20120003158-A1 | Biomarkers for Inflammatory Bowel Disease and Methods Using the Same | METABOLON, INC. | 2012-01-05 | — | — | US | claimed |
| US-20100273207-A1 | Methods for Diagnosis of Sepsis and Risk of Death | LANGLEY RAYMOND | 2010-10-28 | — | — | US | claimed |
| WO-2010124269-A1 | METHODS FOR DIAGNOSIS OF SEPSIS AND RISK OF DEATH | NATIONAL CENTER FOR GENOME RESOURCES (US) | 2010-10-28 | — | — | WO | claimed |