Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129143 | 0.76 | LTA4H (0.43) | LTA4HCA4AOC3ALDH1A1KDM4E | |
| SCHEMBL25566852 | 0.73 | LTA4H (0.33) | LTA4HCA4AOC3 | |
| SCHEMBL18672790 | 0.73 | LTA4H (0.43) | LTA4HMAOBALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL9945371 | 0.71 | LTA4H (0.38) | LTA4HMAOBCA4ALDH1A1CHRNB2 | |
| SCHEMBL16760862 | 0.71 | CA4 (0.42) | LTA4HCA4ALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL28078005 | 0.69 | LTA4H (0.42) | LTA4HCA4AOC3SMN1; SMN2CHRNB2 | |
| SCHEMBL15242512 | 0.69 | MEN1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL16506381 | 0.69 | MEN1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL16506380 | 0.69 | MEN1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAMEN1 | |
| SCHEMBL28231064 | 0.69 | LTA4H (0.36) | LTA4HMAOBCA4AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023843-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1,2,3-TRIAZOL-2-YL)PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-02-11 | — | — | WO | disclosed |