SCHEMBL22969288

SCHEMBL22969288

O=C1N(Cl)CCN1CCOc1ccc2ccccc2c1C#[N+][O-]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.33
KMT2A Q03164 6/20 0.33
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
PKM P14618 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HRH3 Q9Y5N1 5/20 0.32
HTR2A P28223 2/20 0.32
HTR7 P34969 2/20 0.32
HTR6 P50406 2/20 0.32
OPRK1 P41145 1/20 0.32
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29053593 0.90 MEN1 (0.31) MEN1KMT2ANPC1RAB9A
SCHEMBL22969623 0.90 CNR1 (0.35) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL29697577 0.86 MMP3 (0.35) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL21925267 0.82 BRD4 (0.41) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL22969208 0.78 MEN1 (0.33) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL2430976 0.75 KCNA3 (0.43) GAACNR1CNR2TDP1HRH3
SCHEMBL29053591 0.73 BRD4 (0.40) GAA
SCHEMBL12290140 0.73 MAPT (0.36) ALDH1A1KDM4ENPC1NPSR1LMNA
SCHEMBL22969498 0.72 PDK2 (0.39) MEN1KMT2AALDH1A1KDM4EPKM
SCHEMBL22969290 0.70 P2RY12 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4010381-B1 POLYMER HAVING SPECIFIC N-SUBSTITUTED IMIDAZOLIDINONE PENDANT FUNCTIONAL GROUPS MICHELIN & CIE (FR) 2025-04-16 EP disclosed
EP-4010380-B1 COMPOSITION BASED ON AT LEAST ONE COMPOUND HAVING AN N-SUBSTITUTED IMIDAZOLIDINONE FUNCTION MICHELIN & CIE (FR) 2023-10-04 EP disclosed
EP-4010380-B1 COMPOSITION BASED ON AT LEAST ONE COMPOUND HAVING AN N-SUBSTITUTED IMIDAZOLIDINONE FUNCTION MICHELIN & CIE (FR) 2023-10-04 EP disclosed
CN-114269826-B Compositions based on at least one compound with N-substituted imidazolidone functions 米其林集团总公司 2023-09-01 CN disclosed
CN-114206949-B Polymers having specific N-substituted imidazolidone side chain functionalities 米其林集团总公司 2023-08-18 CN disclosed
EP-4010381-A1 POLYMER HAVING SPECIFIC N-SUBSTITUTED IMIDAZOLIDINONE PENDANT FUNCTIONAL GROUPS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-06-15 EP disclosed
EP-4010321-A1 MOLECULE HAVING A NITRILE OXIDE FUNCTION ARKEMA FRANCE (FR) 2022-06-15 EP disclosed
EP-4010380-A1 COMPOSITION BASED ON AT LEAST ONE COMPOUND HAVING AN N-SUBSTITUTED IMIDAZOLIDINONE FUNCTION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-06-15 EP disclosed
CN-114269826-A Composition based on at least one compound having an N-substituted imidazolidinone function 米其林集团总公司 2022-04-01 CN disclosed
CN-114174268-A Molecules having nitrile oxide functional groups 阿科玛法国公司 2022-03-11 CN disclosed
WO-2021023949-A1 COMPOSITION BASED ON AT LEAST ONE COMPOUND HAVING AN N-SUBSTITUTED IMIDAZOLIDINONE FUNCTION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-02-11 WO disclosed
WO-2021023948-A1 POLYMER HAVING SPECIFIC N-SUBSTITUTED IMIDAZOLIDINONE PENDANT FUNCTIONAL GROUPS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-02-11 WO disclosed