SCHEMBL22969334

SCHEMBL22969334

Cc1cc(C)cc(-c2nc3c4nc(-c5cc(C)cc(C)c5)c(-c5cc(C)cc(C)c5)nc4c4nc(-c5cc(C)cc(C)c5)c(-c5cc(C)cc(C)c5)nc4c3nc2-c2cc(C)cc(C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.46
ADORA1 P30542 2/20 0.46
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
NPC1 O15118 1/20 0.34
GAA P10253 1/20 0.34
RAB9A P51151 1/20 0.34
NOS3 P29474 2/20 0.33
NOS2 P35228 2/20 0.33
NOS1 P29475 1/20 0.33
NOTUM Q6P988 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
MAPT P10636 1/20 0.32
CCR1 P32246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16652085 0.79 ADORA2A (0.52) ADORA2AADORA1ALDH1A1TSHRKDM4E
SCHEMBL4546893 0.75 ADORA1 (0.68) ADORA2AADORA1ALDH1A1KDM4EL3MBTL1
SCHEMBL13700767 0.75 ADORA1 (0.68) ADORA2AADORA1ALDH1A1KDM4EL3MBTL1
SCHEMBL4546894 0.75 ADORA1 (0.68) ADORA2AADORA1ALDH1A1KDM4EL3MBTL1
SCHEMBL16291636 0.75 TDP1 (0.61) ADORA2AADORA1ALDH1A1KDM4EL3MBTL1
SCHEMBL3630212 0.74 RAB9A (0.50) ADORA2AADORA1ALDH1A1KDM4ENPC1
SCHEMBL15051484 0.74 ADORA2A (0.40) ADORA2AADORA1ALDH1A1NPC1RAB9A
SCHEMBL25987637 0.74 JAK3 (0.41) ADORA2AADORA1ALDH1A1NOS3NOS2
SCHEMBL4546872 0.72 MEN1 (0.38) ADORA2AADORA1ALDH1A1TSHRKDM4E
SCHEMBL22969696 0.72 TDP1 (0.58) ADORA2AALDH1A1KDM4EL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11778894-B2 Boron-containing organic light-emitting diode device and preparation method thereof JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11778894-B2 Boron-containing organic light-emitting diode device and preparation method thereof JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20210043841-A1 BORON-CONTAINING ORGANIC LIGHT-EMITTING DIODE DEVICE AND PREPARATION METHOD THEREOF VALIANT CO., LTD. (CN) 2021-02-11 US disclosed