Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20974881 | 0.84 | NOTUM (0.38) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL21718958 | 0.78 | — | — | |
| SCHEMBL28058104 | 0.74 | NOTUM (0.32) | NOTUM | |
| SCHEMBL21120990 | 0.74 | NOTUM (0.33) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL19948107 | 0.74 | NOTUM (0.33) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL22043375 | 0.72 | — | — | |
| SCHEMBL20457489 | 0.71 | NOTUM (0.32) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL21598617 | 0.70 | CYP11B2 (0.37) | NOTUMCYP11B1CYP11B2 | |
| SCHEMBL23351548 | 0.69 | NOTUM (0.31) | NOTUM | |
| SCHEMBL20288392 | 0.69 | PDE2A (0.33) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023247-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | WO | disclosed |