Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.40 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27230441 | 0.87 | KRAS (0.40) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL29039717 | 0.87 | KRAS (0.40) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL27210008 | 0.87 | KRAS (0.40) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19617686 | 0.83 | KRAS (0.42) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19637829 | 0.83 | KRAS (0.42) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL29493372 | 0.83 | KRAS (0.42) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL23074825 | 0.81 | PARP1 (0.39) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19948615 | 0.81 | PARP1 (0.46) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL24528933 | 0.81 | KRAS (0.61) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL23075034 | 0.80 | NR1H2 (0.42) | KRASVHLCDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023247-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | WO | disclosed |