Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24453790 | 0.98 | TOP1 (0.47) | TOP1BRD4ATRPIM1PIM2 | |
| SCHEMBL24454362 | 0.96 | TOP1 (0.46) | TOP1BRD4ATRPIM1PIM2 | |
| SCHEMBL24475526 | 0.96 | BRD4 (0.43) | TOP1BRD4ATRCYP3A4CYP2D6 | |
| SCHEMBL22281865 | 0.95 | TOP1 (0.51) | TOP1PIM1PIM2CYP3A4CYP2D6 | |
| SCHEMBL22282249 | 0.95 | TOP1 (0.51) | TOP1ATRPIM1PIM2CYP3A4 | |
| SCHEMBL24475769 | 0.94 | TOP1 (0.50) | TOP1PIM1PIM2CYP3A4CYP2D6 | |
| SCHEMBL24453749 | 0.94 | TOP1 (0.47) | TOP1BRD4ATRCYP3A4CYP2D6 | |
| SCHEMBL24454201 | 0.94 | CYP3A4 (0.42) | TOP1BRD4CYP3A4CYP2D6KDM4E | |
| SCHEMBL24454170 | 0.94 | TOP1 (0.50) | TOP1PIM1PIM2CYP3A4CYP2D6 | |
| SCHEMBL22282257 | 0.94 | TOP1 (0.50) | TOP1PIM1PIM2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220165962-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | LT MATERIALS CO., LTD. (KR) | 2022-05-26 | — | — | US | disclosed |
| WO-2021025356-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | 엘티소재주식회사 | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220165962-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME | CRY1, CYP1A1, CYP1B1 | TOP1 1363/4885BRD4 912/4885ATR 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.