SCHEMBL2297080

SCHEMBL2297080

CCC(OCC1CO1)[Si](OC)(OC)OC.[SiH4]

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23673323 0.98 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28764 0.98 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL1904684 0.98 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
Methyl Alcohol SCHEMBL28322456 0.95 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL9561821 0.93 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5597188 0.90 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1
SCHEMBL27766730 0.88 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL3295508 0.88 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28159646 0.86 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28444841 0.85 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10413935-B2 Free-radical polymerization methods and articles thereby 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-09-17 US disclosed
US-20170246660-A1 FREE-RADICAL POLYMERIZATION METHODS AND ARTICLES THEREBY 3M INNOVATIVE PROPERTIES COMPANY 2017-08-31 US disclosed
US-20170217137-A1 POLYMER-GLASS-POLYMER GAS BARRIER LAMINATE VITNER ASHER (IL) 2017-08-03 US disclosed
EP-3169517-A1 POLYMER-GLASS-POLYMER GAS BARRIER LAMINATE Vitner, Asher (IL) 2017-05-24 EP disclosed
WO-2016009435-A1 POLYMER-GLASS-POLYMER GAS BARRIER LAMINATE VITNER ASHER (IL) 2016-01-21 WO disclosed
US-8916624-B2 Dental compositions crosslinkable/polymerizable by cationic process BLUESTAR SILICONES FRANCE SAS (FR) 2014-12-23 US disclosed
US-20110189632-A1 DENTAL COMPOSITIONS CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2011-08-04 US disclosed
US-7740482-B2 Stable cationically crosslinkable/polymerizable dental composition with a high filler content BLUESTAR SILICONES FRANCE (FR) 2010-06-22 US disclosed
EP-1745083-B1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION BLUESTAR SILICONES FRANCE (FR) 2009-12-16 EP disclosed
EP-2043588-B1 DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2009-11-18 EP disclosed
EP-2043588-A2 DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS Bluestar Silicones France (FR) 2009-04-08 EP disclosed
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2008-11-20 US disclosed
WO-2008009718-A2 DENTAL COMPOSITION CROSSLINKABLE/POLYMERIZABLE BY CATIONIC PROCESS BLUESTAR SILICONES FRANCE (FR) 2008-01-24 WO disclosed
EP-1745083-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION Rhodia Chimie (FR) 2007-01-24 EP disclosed
WO-2005121200-A1 HIGHLY-CHARGED STABLE DENTAL COMPOSITION WHICH MAY BE CROSS-LINKED/POLYMERISED BY CATIONIC REACTION RHODIA CHIMIE (FR) 2005-12-22 WO disclosed
US-20050261390-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RHODIA CHIMIE (FR) 2005-11-24 US disclosed
US-6144106-A Electronic coatings DOW CORNING CORPORATION (US) 2000-11-07 US disclosed
EP-0834918-A1 Multilayer tamperproof electronic coating DOW CORNING CORPORATION (US) 1998-04-08 EP disclosed
US-5711987-A Electronic coatings DOW CORNING CORPORATION (US) 1998-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287562-A1 Stable cationically crosslinkable/polymerizable dental composition with a high filler content RFC1, RFC2, HNRNPC ALDH1A1 2637/4885SMN1; SMN2 4071/4885TDP1 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.