Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.57 |
| ▸ | XDH | P47989 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156688 | 0.86 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29773082 | 0.86 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL26658515 | 0.81 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL130407 | 0.73 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL23059282 | 0.71 | PI4KB (0.54) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL179551 | 0.71 | PI4KB (0.54) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL15627374 | 0.71 | PI4KB (0.54) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29139991 | 0.69 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL1597202 | 0.69 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL30788410 | 0.69 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022718-A1 | APPLICATION OF PYRAZOLOPYRIMIDINE COMPOUND IN PREPARATION OF DRUGS FOR PREVENTING/TREATING TUMORS | 四川大学华西医院 | 2021-02-11 | — | — | WO | disclosed |