Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21428992 | 0.90 | PPARD (0.42) | PPARDTSHRMAPTPOLB | |
| SCHEMBL22973754 | 0.87 | PPARD (0.39) | PPARDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22973713 | 0.84 | THRA (0.36) | PPARDTHRATHRBMAPT | |
| SCHEMBL22973762 | 0.82 | PPARD (0.36) | PPARDHTT | |
| SCHEMBL23005854 | 0.80 | PPARD (0.34) | PPARD | |
| SCHEMBL23006003 | 0.76 | PPARD (0.46) | PPARDTSHRMAPTPOLBHTT | |
| SCHEMBL31418408 | 0.75 | PPARD (0.35) | PPARDTSHR | |
| SCHEMBL21428989 | 0.75 | PPARD (0.35) | PPARDTSHR | |
| SCHEMBL29108971 | 0.75 | PPARD (0.36) | PPARDTSHRMAPTPOLBHTT | |
| SCHEMBL21408255 | 0.74 | CYP4A11 (0.36) | PPARDTSHRMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778612-A1 | PHOSPHATE DERIVATIVES AND USE THEREOF | Zhu, Qing (CN) | 2021-02-17 | — | — | EP | disclosed |