SCHEMBL22975871

SCHEMBL22975871

CC1(C)O[C@@H]2[C@H](O1)[C@@H](CS)O[C@H]2n1ncc2c(NC3CCCC3)nc(Cl)nc21

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NT5E P21589 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31757506 0.91 NT5E (0.56) NT5E
SCHEMBL20180063 0.91 NT5E (0.56) NT5E
SCHEMBL20180062 0.90 NT5E (0.57) NT5E
SCHEMBL23006827 0.85 NT5E (0.54) NT5E
SCHEMBL22614528 0.85 NT5E (0.57) NT5E
SCHEMBL21839468 0.84 ADORA3 (0.42) NT5E
SCHEMBL26720428 0.84 NT5E (0.54) NT5E
SCHEMBL20524245 0.83 NT5E (0.76) NT5E
SCHEMBL22975424 0.83 NT5E (0.59) NT5E
SCHEMBL20180065 0.83 NT5E (0.51) NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674481-A2 CD73 INHIBITORS Oric Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
US-20250368677-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2025-12-04 US disclosed
EP-3787635-B1 CD73 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2025-09-17 EP disclosed
US-20240124512-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2024-04-18 US disclosed
US-11807658-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
US-11807658-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
US-20220220147-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2022-07-14 US disclosed
US-11325938-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2022-05-10 US disclosed
US-11325938-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2022-05-10 US disclosed
EP-3787635-A1 CD73 INHIBITORS Oric Pharmaceuticals, Inc. (US) 2021-03-10 EP disclosed
CN-112423764-A CD73 inhibitor 欧瑞克制药公司 2021-02-26 CN disclosed
US-20210047359-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2021-02-18 US disclosed
US-20210047359-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2021-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124512-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-11807658-B2 CD73 inhibitors ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20220220147-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-11325938-B2 CD73 inhibitors ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20250368677-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20210047359-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.