Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT7 | Q11130 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559892 | 0.89 | CHRM2 (0.37) | FUT7AKT1GRIN2DGRIN2AGRIN2B | |
| SCHEMBL7159798 | 0.85 | SLC6A2 (0.41) | CHRM5CHRM1HIF1A | |
| SCHEMBL7161094 | 0.85 | SLC6A2 (0.41) | CHRM5CHRM1HIF1A | |
| SCHEMBL7159573 | 0.85 | SLC6A2 (0.41) | CHRM5CHRM1HIF1A | |
| SCHEMBL9059073 | 0.81 | SKP2 (0.39) | CHRM5CHRM1SIGMAR1 | |
| SCHEMBL7160512 | 0.77 | SLC6A2 (0.40) | CHRM5CHRM1HIF1A | |
| SCHEMBL7154930 | 0.77 | SLC6A2 (0.40) | CHRM5CHRM1HIF1A | |
| SCHEMBL7159772 | 0.77 | SLC6A2 (0.40) | CHRM5CHRM1HIF1A | |
| SCHEMBL1325123 | 0.76 | AKT1 (0.33) | AKT1HIF1AEPAS1 | |
| SCHEMBL8938190 | 0.75 | RAB9A (0.32) | CHRM5CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251737-B1 | COMPOSITIONS TREATED TO INACTIVATE INFECTIOUS PROTEINS | UNIV CALIFORNIA (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1251737-A2 | COMPOSITIONS TREATED TO INACTIVATE INFECTIOUS PROTEINS | The Regents of the University of California (US) | 2002-10-30 | — | — | EP | claimed |
| WO-2001054736-A2 | COMPOSITIONS TREATED TO INACTIVATE INFECTIOUS PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-08-02 | — | — | WO | claimed |
| EP-2283130-B1 | Dispersin B(TM), 5-fluorouracil, deoxyribonuclease I and proteinase K-based antibiofilm compositions and uses thereof | KANE BIOTECH INC (CA) | 2014-09-10 | — | — | EP | disclosed |
| US-8821862-B2 | Soluble β-N-acetylglucosaminidase based antibiofilm compositions and uses thereof | KANE BIOTECH INC. (CA) | 2014-09-02 | — | — | US | disclosed |
| US-8617542-B2 | DispersinB™, 5-fluorouracil, deoxyribonuclease I and proteinase K-based antibiofilm compositions and uses thereof | KANE BIOTECH INC. (CA) | 2013-12-31 | — | — | US | disclosed |
| US-20120258089-A1 | SOLUBLE BETA-N-ACETYLGLUCOSAMINIDASE BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF | KANE BIOTECH INC. (CA) | 2012-10-11 | — | — | US | disclosed |
| EP-1919932-B1 | PRION INACTIVATION | RIESNER DETLEF (DE) | 2012-01-04 | — | — | EP | disclosed |
| US-20110086101-A1 | Dispersinb, 5-Fluorouracil, Deoxyribonuclease I and Proteinase K-Based Antibiofilm Compositions and Uses Thereof | PIVOT FINANCIAL INC. (CA) | 2011-04-14 | — | — | US | disclosed |
| EP-2283130-A1 | DISPERSINBtm, 5-FLUOROURACIL, DEOXYRIBONUCLEASE I AND PROTEINASE K-BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF | Kane Biotech Inc. (CA) | 2011-02-16 | — | — | EP | disclosed |
| US-20110008402-A1 | SOULUBLE B-N-ACETYLGLUCOSEAMINIDASE BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF | KANE BIOTECH INC. (CA) | 2011-01-13 | — | — | US | disclosed |
| WO-2003077835-A9 | SODIUM DODECYL SULFATE COMPOSITIONS FOR INACTIVATING PRIONS | UNIV CALIFORNIA (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-1414297-A2 | SODIUM DODECYL SULFATE COMPOSITIONS FOR INACTIVATING PRIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6719988-B2 | MIXTURE CONTAINING SOLVENT, ACID; COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-13 | — | — | US | disclosed |
| US-6720355-B2 | ANTISEPTICS; ACIDITY PH; DESTROYING INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-13 | — | — | US | disclosed |
| WO-2003077835-A2 | SODIUM DODECYL SULFATE COMPOSITIONS FOR INACTIVATING PRIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-09-25 | — | — | WO | disclosed |
| US-20030004312-A1 | Sodium dodecyl sulfate compositions for inactivating prions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-02 | — | — | US | disclosed |
| EP-1251737-A2 | COMPOSITIONS TREATED TO INACTIVATE INFECTIOUS PROTEINS | The Regents of the University of California (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020041859-A1 | Antiseptic compositions for inactivating prions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-04-11 | — | — | US | disclosed |
| WO-2001054736-A2 | COMPOSITIONS TREATED TO INACTIVATE INFECTIOUS PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-08-02 | — | — | WO | disclosed |