SCHEMBL22978403

SCHEMBL22978403

FC(F)(F)c1ccc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.71
ALDH1A1 P00352 1/20 0.54
TSHR P16473 1/20 0.54
BACE1 P56817 2/20 0.53
ESR1 P03372 1/20 0.50
TNKS O95271 1/20 0.46
WNT3A P56704 1/20 0.46
TNKS2 Q9H2K2 1/20 0.46
SCN2A Q99250 2/20 0.46
ABCG2 Q9UNQ0 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2E1 P05181 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP4B1 P13584 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214763 0.96 KIF11 (0.62) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL15137878 0.89 KIF11 (0.57) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL27942366 0.89 ESR1 (0.57) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL13158727 0.89 KIF11 (0.62) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL4400718 0.89 KIF11 (0.62) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL10063996 0.88 KIF11 (0.55) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL10063954 0.88 KIF11 (0.55) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL4402357 0.88 KIF11 (0.60) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL10063973 0.88 KIF11 (0.55) KIF11ALDH1A1TSHRBACE1ESR1
SCHEMBL10063906 0.86 KIF11 (0.58) KIF11ALDH1A1TSHRBACE1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250120252-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-04-10 US disclosed
US-12178064-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2024-12-24 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed
CN-112135808-A Materials for forming nucleation inhibiting coatings and devices incorporating same OTI照明公司 2020-12-25 CN disclosed