SCHEMBL22978404

SCHEMBL22978404

c1cc(-c2cccc3ccccc23)cc(-c2c3ccccc3c(-c3cc4ccccc4c4ccccc34)c3ccccc23)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ HSD17B10 Q99714 3/20 0.44
▸ HPGD P15428 3/20 0.44
▸ HIF1A Q16665 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ MAPK1 P28482 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ CYP11B1 P15538 1/20 0.42
▸ MCL1 Q07820 1/20 0.41
▸ ACMSD Q8TDX5 1/20 0.41
▸ CA12 O43570 2/20 0.40
▸ CA1 P00915 2/20 0.40
▸ CA2 P00918 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ SOS1 Q07889 1/20 0.40
▸ CYP1B1 Q16678 1/20 0.39
▸ GPR84 Q9NQS5 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30350883 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL19199293 0.90 HPRT1 (0.47) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL22978414 0.90 MCL1 (0.45) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL30150715 0.90 MCL1 (0.45) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL26047995 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL22147814 0.88 CA12 (0.46) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL25634450 0.88 MCL1 (0.44) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL4316197 0.88 CYP11B1 (0.53) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL19199467 0.87 MCL1 (0.44) ALDH1A1HSD17B10HPGDHIF1ATSHR
SCHEMBL24173970 0.86 CYP11B1 (0.45) ALDH1A1HSD17B10HPGDHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492313-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2025-12-09 — — US disclosed
US-20250120252-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2025-04-10 — — US disclosed
US-12178064-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2024-12-24 — — US disclosed
US-20240074230-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2024-02-29 — — US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 — — US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 — — US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 — — US disclosed
US-11730012-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-08-15 — — US disclosed
US-20220246887-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LIMIONICS, INC. (CA) 2022-08-04 — — US disclosed
CN-113785411-A Material for forming nucleation inhibiting coatings and apparatus incorporating the same OTI照明公司 2021-12-10 — — CN disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 — — US disclosed
CN-112135808-A Materials for forming nucleation inhibiting coatings and devices incorporating same OTI照明公司 2020-12-25 — — CN disclosed
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