Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989544 | 0.71 | CTDSP1 (0.40) | CTDSP1TSHR | |
| SCHEMBL845907 | 0.71 | KDM4E (0.35) | KDM4EKMT2AMAPTMEN1GAA | |
| SCHEMBL27226042 | 0.70 | ALDH1A1 (0.42) | KDM4EGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL26081244 | 0.70 | TSHR (0.46) | KDM4ECTDSP1KMT2AMAPTMEN1 | |
| SCHEMBL30937589 | 0.69 | CTDSP1 (0.36) | CTDSP1MAPTALDH1A1 | |
| SCHEMBL27226523 | 0.68 | KDM5B (0.41) | KDM4EKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL30815610 | 0.68 | KDM5B (0.41) | KDM4EKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL13082294 | 0.67 | — | — | |
| SCHEMBL13075122 | 0.66 | PARP1 (0.37) | — | |
| SCHEMBL25188555 | 0.66 | HCRTR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |