Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19491472 | 0.85 | KIF11 (0.35) | KIF11IDO1DDR1SCN9ANPSR1 | |
| SCHEMBL857212 | 0.83 | SCN5A (0.32) | IDO1SCN9A | |
| SCHEMBL16637432 | 0.82 | KIF11 (0.33) | KIF11DDR1NOTUMNPSR1 | |
| SCHEMBL15599160 | 0.79 | SCN9A (0.39) | SCN9A | |
| SCHEMBL24566218 | 0.76 | IDO1 (0.44) | KIF11IDO1DDR1NPSR1 | |
| SCHEMBL1445686 | 0.76 | IDO1 (0.59) | IDO1 | |
| SCHEMBL1230228 | 0.73 | S1PR4 (0.32) | DDR1NOTUMNPSR1 | |
| SCHEMBL16398716 | 0.73 | SRD5A2 (0.47) | KIF11IDO1NPSR1 | |
| SCHEMBL16399421 | 0.73 | POLQ (0.43) | IDO1 | |
| SCHEMBL32682782 | 0.73 | SRD5A2 (0.47) | KIF11IDO1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |