Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15512775 | 0.82 | SMN1; SMN2 (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL143218 | 0.82 | SMN1; SMN2 (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL4467232 | 0.80 | PPM1D (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL4371165 | 0.77 | RECQL (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL6026102 | 0.77 | RECQL (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL4370444 | 0.77 | RECQL (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL4371444 | 0.77 | RECQL (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL2958649 | 0.77 | RECQL (0.33) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL2956240 | 0.76 | RECQL (0.32) | HSD17B10RECQLUSP2SMN1; SMN2HPGD | |
| SCHEMBL4370286 | 0.76 | RECQL (0.32) | HSD17B10RECQLUSP2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010080-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028643-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |