Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PPM1D | O15297 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15512775 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2HSD17B10RECQLUSP2PPM1D | |
| SCHEMBL4371143 | 0.88 | RECQL (0.32) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL2956240 | 0.88 | RECQL (0.32) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL4370286 | 0.88 | RECQL (0.32) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL2964589 | 0.88 | RECQL (0.32) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL2593873 | 0.87 | USP2 (0.32) | SMN1; SMN2USP2PPM1DCHRM2CHRM1 | |
| SCHEMBL6052845 | 0.87 | PPM1D (0.34) | SMN1; SMN2PPM1D | |
| SCHEMBL22980250 | 0.82 | HSD17B10 (0.32) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL28735702 | 0.82 | HSD17B10 (0.36) | SMN1; SMN2HSD17B10RECQLUSP2HPGD | |
| SCHEMBL29519627 | 0.82 | HSD17B10 (0.36) | SMN1; SMN2HSD17B10RECQLUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058989-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | RECQL, BLVRB, NQO2 | SMN1; SMN2 3896/4885HSD17B10 1844/4885RECQL 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.