Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017876 | 0.72 | GAA (0.36) | GAAPDE3BPDE3ALMNAHTT | |
| SCHEMBL19857363 | 0.72 | BAZ2B (0.42) | GAAPDE3BPDE3AHTTTSHR | |
| SCHEMBL17910054 | 0.69 | SMN1; SMN2 (0.57) | GAAPDE3BPDE3ALMNAHTT | |
| SCHEMBL17826992 | 0.68 | TRIM24 (0.41) | GAASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL1396725 | 0.67 | — | — | |
| SCHEMBL16539713 | 0.66 | LMNA (0.55) | PDE3BPDE3ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18542552 | 0.65 | — | — | |
| SCHEMBL14463094 | 0.64 | — | — | |
| SCHEMBL1176138 | 0.64 | — | — | |
| SCHEMBL3131723 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010311-A1 | POLYISOCYANATE AND PROCESS FOR PREPARING THE SAME | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028300-A1 | POLYISOCYANATE AND PROCESS FOR PREPARING THE SAME | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-02-18 | — | — | WO | disclosed |