SCHEMBL22981

SCHEMBL22981

COC(=O)c1ccc(C(=O)OC)c(N/N=C(/C(C)=O)C(=O)Nc2ccc([N+](=O)[O-])cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.52
KMT2A Q03164 10/20 0.52
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 2/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MAPT P10636 9/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPK1 P28482 2/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 4/20 0.43
TP53 P04637 1/20 0.42
POLB P06746 2/20 0.42
GAA P10253 3/20 0.42
HDAC1 Q13547 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052753 0.91 KDM4E (0.52) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL16523 0.91 KDM4E (0.52) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL16353323 0.89 MEN1 (0.52) MEN1KMT2AALDH1A1HPGDMAPT
SCHEMBL15246775 0.86 KDM4E (0.48) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL13092164 0.86 KDM4E (0.48) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL13111768 0.86 KDM4E (0.48) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL12677172 0.86 KDM4E (0.48) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL14960667 0.86 KDM4E (0.48) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL12299544 0.86 KDM4E (0.48) KMT2AALDH1A1KDM4EHPGDCASP1
SCHEMBL12393179 0.86 KDM4E (0.48) KMT2AALDH1A1KDM4EHPGDCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9618867-B2 Pigment dispersion and toner CANON KABUSHIKI KAISHA (JP) 2017-04-11 US disclosed
US-9618867-B2 Pigment dispersion and toner CANON KABUSHIKI KAISHA (JP) 2017-04-11 US disclosed
EP-2843473-B1 Toner CANON KK (JP) 2016-11-02 EP disclosed
US-20160246200-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2016-08-25 US disclosed
US-20160246200-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2016-08-25 US disclosed
US-9249308-B2 Compound having bisazo dye skeleton, pigment composition containing the same, pigment dispersion, ink, and color filter resist composition CANON KABUSHIKI KAISHA (JP) 2016-02-02 US disclosed
US-9249308-B2 Compound having bisazo dye skeleton, pigment composition containing the same, pigment dispersion, ink, and color filter resist composition CANON KABUSHIKI KAISHA (JP) 2016-02-02 US disclosed
US-9229345-B2 Toner CANON KABUSHIKI KAISHA (JP) 2016-01-05 US disclosed
US-9229345-B2 Toner CANON KABUSHIKI KAISHA (JP) 2016-01-05 US disclosed
US-9176407-B2 Toner and method for manufacturing toner particles CANON KABUSHIKI KAISHA (JP) 2015-11-03 US disclosed
WO-2013069815-A1 NOVEL COMPOUND HAVING BISAZO DYE SKELETON, PIGMENT COMPOSITION CONTAINING THE SAME, PIGMENT DISPERSION, INK, AND COLOR FILTER RESIST COMPOSITION CANON KABUSHIKI KAISHA (JP) 2013-05-16 WO disclosed
WO-2013069816-A1 TONER AND METHOD FOR MANUFACTURING TONER PARTICLES CANON KABUSHIKI KAISHA (JP) 2013-05-16 WO disclosed
US-20130095421-A1 TONER INCLUDING COMPOUND HAVING BISAZO SKELETON CANON KABUSHIKI KAISHA (JP) 2013-04-18 US disclosed
US-8377616-B2 AZO compound, and pigment dispersant, pigment composition, pigment dispersion and toner including the azo compound CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-8377616-B2 AZO compound, and pigment dispersant, pigment composition, pigment dispersion and toner including the azo compound CANON KABUSHIKI KAISHA (JP) 2013-02-19 US disclosed
US-20120231388-A1 AZO COMPOUND, AND PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION AND TONER INCLUDING THE AZO COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-09-13 US disclosed
US-20120231388-A1 AZO COMPOUND, AND PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION AND TONER INCLUDING THE AZO COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-09-13 US disclosed
US-20120094226-A1 AZO COMPOUND, AND PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION AND TONER INCLUDING THE AZO COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed
US-20120094226-A1 AZO COMPOUND, AND PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION AND TONER INCLUDING THE AZO COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-04-19 US disclosed
WO-2012026607-A1 AZO COMPOUND, AND PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION AND TONER INCLUDING THE AZO COMPOUND CANON KABUSHIKI KAISHA (JP) 2012-03-01 WO disclosed