Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 10/20 | 0.41 |
| ▸ | MMP1 | P03956 | 9/20 | 0.41 |
| ▸ | MMP3 | P08254 | 8/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP8 | P22894 | 6/20 | 0.40 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP20 | O60882 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463831 | 0.87 | MAPT (0.39) | RNPEPMMP9MMP1MMP3MME | |
| SCHEMBL5465868 | 0.79 | RNPEP (0.54) | RNPEPMMEACECPA1ACE2 | |
| SCHEMBL5471418 | 0.77 | MAPT (0.39) | RNPEPMMP9MMP1MMP3MME | |
| SCHEMBL16300127 | 0.75 | MMP9 (0.42) | RNPEPMMP9MMP1MMP3MMP2 | |
| SCHEMBL4660964 | 0.75 | MMP9 (0.42) | RNPEPMMP9MMP1MMP3MMP2 | |
| SCHEMBL29060619 | 0.75 | — | — | |
| SCHEMBL14365019 | 0.75 | MMP9 (0.42) | RNPEPMMP9MMP1MMP3MMP2 | |
| SCHEMBL18391421 | 0.73 | MMP9 (0.44) | MMP9MMP1MMP3MMP2MMP8 | |
| SCHEMBL5470099 | 0.73 | RNPEP (0.37) | RNPEPMMP9MMP1MMP3MME | |
| SCHEMBL26004765 | 0.73 | MMP9 (0.44) | MMP9MMP1MMP3MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010348-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028323-A1 | (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-02-18 | — | — | WO | disclosed |