Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | HEXA | P06865 | 7/20 | 0.44 |
| ▸ | HEXB | P07686 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21161647 | 0.94 | TDP1 (0.50) | TDP1MPORAD52CYP1B1HEXA | |
| SCHEMBL21161649 | 0.84 | MPO (0.51) | TDP1MPORAD52CYP1B1HEXA | |
| SCHEMBL13829105 | 0.75 | ERCC1 (0.50) | TDP1RAD52CYP1B1HEXAHEXB | |
| SCHEMBL7706739 | 0.75 | ERCC1 (0.57) | TDP1MPORAD52CYP1B1HEXA | |
| SCHEMBL5681175 | 0.74 | CYP3A4 (0.46) | TDP1KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL28870673 | 0.74 | ERCC1 (0.53) | TDP1RAD52CYP1B1HEXAHEXB | |
| SCHEMBL7709925 | 0.74 | ERCC1 (0.55) | TDP1MPORAD52CYP1B1HEXA | |
| SCHEMBL11709886 | 0.74 | PRMT1 (0.49) | TDP1CYP1B1KMT2AMEN1CYP1A2 | |
| SCHEMBL19015165 | 0.73 | TDP1 (0.45) | TDP1MPORAD52CYP1B1HEXA | |
| SCHEMBL7709551 | 0.72 | ERCC1 (0.50) | RAD52CYP1B1HEXAHEXBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021029158-A1 | SULFONAMIDE COMPOUND, NONIONIC PHOTOACID GENERATOR, AND PHOTOLITHOGRAPHY RESIN COMPOSITION | サンアプロ株式会社 | 2021-02-18 | — | — | WO | disclosed |