SCHEMBL22982002

SCHEMBL22982002

O=C(O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](n2cc(-c3cc(F)cc(F)c3)nn2)[C@H]1O

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 20/20 0.70
LGALS1 P09382 9/20 0.70
LGALS8 O00214 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22542393 0.91 LGALS3 (0.72) LGALS3LGALS1LGALS8
SCHEMBL22982173 0.91 LGALS3 (0.71) LGALS3LGALS1
SCHEMBL22981168 0.89 LGALS3 (0.60) LGALS3LGALS1
SCHEMBL22982172 0.89 LGALS3 (0.61) LGALS3LGALS1
SCHEMBL25858142 0.83 LGALS3 (0.61) LGALS3LGALS1LGALS8
SCHEMBL25855498 0.80 LGALS3 (0.63) LGALS3LGALS1LGALS8
SCHEMBL22247289 0.79 LGALS3 (0.73) LGALS3LGALS1LGALS8
SCHEMBL26727629 0.79 LGALS3 (0.66) LGALS3LGALS1
SCHEMBL22247034 0.79 LGALS3 (0.72) LGALS3LGALS1
SCHEMBL30185321 0.78 LGALS3 (0.82) LGALS3LGALS1LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4013751-B1 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2025-01-22 EP disclosed
EP-4013751-A1 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2022-06-22 EP disclosed
CN-114269737-A 2-hydroxycycloalkane-1-carbamoyl derivatives 爱杜西亚药品有限公司 2022-04-01 CN disclosed
WO-2021028570-A1 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2021-02-18 WO disclosed