Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 13/20 | 1.00 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697644 | 1.00 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29697605 | 0.98 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL22981963 | 0.98 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29697529 | 0.93 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29405453 | 0.93 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL22981999 | 0.93 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29407573 | 0.92 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL29407418 | 0.91 | F11 (0.95) | F11KLKB1 | |
| SCHEMBL22982169 | 0.90 | F11 (0.95) | F11KLKB1 | |
| SCHEMBL29407429 | 0.90 | F11 (0.95) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010333-A1 | PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-15 | — | — | EP | claimed |
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | claimed |
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | claimed |
| EP-4010333-A1 | PLASMA KALLIKREIN INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-15 | — | — | EP | disclosed |
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |