Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2294766 | 0.92 | S1PR1 (0.52) | S1PR1KDM4ERAB9AHSD17B10ALOX15 | |
| SCHEMBL2299676 | 0.90 | S1PR1 (0.58) | S1PR1KDM4ERAB9AHSD17B10ALOX15 | |
| SCHEMBL2298013 | 0.89 | S1PR1 (0.58) | S1PR1KDM4EHSD17B10S1PR3ALDH1A1 | |
| SCHEMBL2300532 | 0.85 | S1PR1 (0.65) | S1PR1KDM4ERAB9AHSD17B10ALOX15 | |
| SCHEMBL1966625 | 0.82 | S1PR1 (0.81) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2294742 | 0.82 | S1PR1 (0.56) | S1PR1KDM4ERAB9AHSD17B10ALOX15 | |
| SCHEMBL2297971 | 0.81 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1649676 | 0.81 | S1PR1 (0.44) | S1PR1KDM4ERAB9AHSD17B10ALOX15 | |
| Ammonia Solution, Strong SCHEMBL27838331 | 0.80 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965196 | 0.80 | S1PR1 (0.69) | S1PR1KDM4EHSD17B10S1PR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200557-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | S1PR2, S1PR3, S1PR1 | S1PR1 3/4885KDM4E 4607/4885RAB9A 3103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.