Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TYMP | P19971 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460809 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL1775528 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL14064188 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL22983972 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL2460807 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL22984023 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL22983968 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL23517951 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL7535874 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL6250998 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519126-A | COMBATTING DISEASES BY BIOCHEMICL INTERVENTION AT THE RNA AND DNA LEVEL | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0558749-A1 | ANTISENSE NUCLEIC ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1993-09-08 | — | — | EP | disclosed |
| EP-0406309-A4 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | — | 1992-08-19 | — | — | EP | disclosed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |
| US-4757055-A | Binding herpes virus with nonionic oligonucleoside alkyl or arylphosphonate complementary to base sequence of virus | THE JOHNS HOPKINS UNIVERSITY (US) | 1988-07-12 | — | — | US | disclosed |
| US-4511713-A | Process for selectively controlling unwanted expression or function of foreign nucleic acids in animal or mammalian cells | THE JOHNS HOPKINS UNIVERSITY (US) | 1985-04-16 | — | — | US | disclosed |