Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22984366 | 0.86 | HTT (0.54) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL22984315 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL17676260 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL22984371 | 0.81 | HTT (0.48) | SMN1; SMN2LMNAHTTL3MBTL1KDM4E | |
| SCHEMBL17676513 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL18656656 | 0.80 | GAA (0.58) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL17676255 | 0.80 | GAA (0.55) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL18656579 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL18642139 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAHTTL3MBTL1GAA | |
| SCHEMBL19723736 | 0.79 | GAA (0.52) | SMN1; SMN2LMNAHTTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | BET1, BRD4, BRD3 | SMN1; SMN2 3362/4885LMNA 1620/4885HTT 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.