Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768316 | 0.92 | KDM4E (0.60) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL19723587 | 0.91 | KMT2A (0.52) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL17676515 | 0.91 | GAA (0.51) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL19723547 | 0.89 | LMNA (0.61) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL19723548 | 0.88 | DDT (0.50) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL18656325 | 0.88 | SMN1; SMN2 (0.48) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL17676260 | 0.88 | SMN1; SMN2 (0.58) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL19723719 | 0.87 | SMN1; SMN2 (0.52) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL18656656 | 0.86 | GAA (0.58) | GAASMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL17676521 | 0.86 | ROCK2 (0.50) | GAASMN1; SMN2LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257854-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2017-12-20 | — | — | EP | disclosed |
| US-9309238-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-04-12 | — | — | US | disclosed |