Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 8/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22984265 | 0.85 | HTT (0.48) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984293 | 0.83 | HTT (0.52) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984310 | 0.79 | HTT (0.46) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984267 | 0.78 | HTT (0.47) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984263 | 0.77 | ALDH1A1 (0.48) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984313 | 0.77 | HTT (0.54) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984245 | 0.76 | HTT (0.55) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984249 | 0.76 | CYP2C9 (0.45) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18642291 | 0.76 | SMN1; SMN2 (0.51) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22984369 | 0.75 | SMN1; SMN2 (0.66) | HTTLMNASMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | BET1, BRD4, BRD3 | HTT 4525/4885LMNA 1620/4885SMN1; SMN2 3362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.