SCHEMBL22985331

SCHEMBL22985331

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccc(C#N)cc2-c2ccc(-c3ccc(C#N)cc3C(F)(F)F)cc2-n2c3ccccc3c3cc(-c4ccc(C)cc4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 7/20 0.38
KIF11 P52732 1/20 0.34
PTGER4 P35408 1/20 0.34
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
PDK2 Q15119 1/20 0.32
RORC P51449 1/20 0.31
NSD2 O96028 1/20 0.31
TRPA1 O75762 2/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
ATM Q13315 1/20 0.30
PGR P06401 1/20 0.30
MAPKAPK2 P49137 1/20 0.30
PDE9A O76083 1/20 0.30
PDE1C Q14123 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22985676 0.96 AR (0.38) ARKIF11PTGER4AKR1C3AKR1C2
SCHEMBL22985004 0.96 AR (0.40) ARKIF11PTGER4AKR1C3AKR1C2
SCHEMBL22985551 0.96 AR (0.40) ARKIF11PTGER4AKR1C3AKR1C2
SCHEMBL22985333 0.95 AR (0.42) ARKIF11AKR1C3AKR1C2PDK2
SCHEMBL20848464 0.95 AR (0.36) ARKIF11PTGER4AKR1C3AKR1C2
SCHEMBL22985555 0.94 AR (0.35) ARKIF11PTGER4AKR1C3AKR1C2
SCHEMBL22985323 0.94 KIF11 (0.39) ARKIF11PTGER4PDK2RORC
SCHEMBL22985326 0.94 AR (0.34) ARKIF11PTGER4PDK2RORC
SCHEMBL22985553 0.93 KIF11 (0.36) ARKIF11PTGER4PDK2PGR
SCHEMBL22985372 0.93 AR (0.42) ARKIF11PTGER4PDK2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 AR 3541/4885KIF11 525/4885PTGER4 3301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.