SCHEMBL22985338

SCHEMBL22985338

N#Cc1ccc(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c(-c2ccc(-c3ccc(C#N)cc3C(F)(F)F)cc2-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.38
ALOX5AP P20292 2/20 0.36
FEN1 P39748 2/20 0.36
AR P10275 5/20 0.33
PTGDR2 Q9Y5Y4 3/20 0.33
DGAT1 O75907 1/20 0.33
SOAT1 P35610 1/20 0.33
KCNH2 Q12809 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
ELANE P08246 2/20 0.32
NSD2 O96028 1/20 0.32
CYP2C9 P11712 1/20 0.32
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848471 0.99 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL21399780 0.97 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL20849523 0.97 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL20848874 0.97 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL22985376 0.97 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL20848719 0.96 KIF11 (0.42) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL22985309 0.96 KIF11 (0.38) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL22985690 0.96 KIF11 (0.40) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL22985329 0.95 KIF11 (0.34) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL21399470 0.95 KIF11 (0.39) KIF11ALOX5APFEN1ARPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 KIF11 525/4885ALOX5AP 2567/4885FEN1 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.