SCHEMBL22985369

SCHEMBL22985369

N#Cc1ccc(-n2c3ccccc3c3cc(C(F)(F)F)ccc32)c(-c2ccc(-c3ccc(C#N)cc3C(F)(F)F)cc2-n2c3ccccc3c3cc(C(F)(F)F)ccc32)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.35
AR P10275 8/20 0.35
ELANE P08246 3/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
PTGDR2 Q9Y5Y4 2/20 0.31
PGR P06401 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20849522 0.98 KIF11 (0.35) KIF11ARELANEALOX5APFEN1
SCHEMBL22985329 0.97 KIF11 (0.34) KIF11ARELANEALOX5APFEN1
SCHEMBL22985583 0.96 KIF11 (0.35) KIF11ARELANEALOX5APFEN1
SCHEMBL20848466 0.96 KIF11 (0.35) KIF11ARELANEALOX5APFEN1
SCHEMBL20848776 0.96 KIF11 (0.35) KIF11ARELANEALOX5APFEN1
SCHEMBL22985564 0.96 KIF11 (0.36) KIF11ARELANEALOX5APFEN1
SCHEMBL22985610 0.96 KIF11 (0.36) KIF11ARELANEALOX5APFEN1
SCHEMBL22985376 0.95 KIF11 (0.39) KIF11ARELANEALOX5APFEN1
SCHEMBL20848973 0.94 KIF11 (0.34) KIF11ARELANEALOX5APFEN1
SCHEMBL22985562 0.94 AR (0.34) KIF11ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 KIF11 525/4885AR 3541/4885ELANE 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.