SCHEMBL22985472

SCHEMBL22985472

N#Cc1ccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5ccccc5)c4cc32)c(-c2cc(-n3c4ccccc4c4cc5c6ccccc6n(-c6ccccc6)c5cc43)ccc2-c2ccc(C#N)cc2C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AR P10275 9/20 0.33
SCN9A Q15858 1/20 0.31
ACP1 P24666 1/20 0.31
ELANE P08246 1/20 0.30
TDP2 O95551 3/20 0.30
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848509 0.94 PPARG (0.33) KDM4EATML3MBTL1ARSCN9A
SCHEMBL22985295 0.92 AR (0.35) ARSCN9AACP1TRPV4
SCHEMBL22985293 0.92 AR (0.35) ARSCN9AACP1TRPV4
SCHEMBL22985177 0.92 AR (0.35) ARSCN9AACP1TRPV4
SCHEMBL20849366 0.91 KDM4E (0.33) KDM4EATML3MBTL1ARACP1
SCHEMBL22985514 0.89 KDM4E (0.35) KDM4EATML3MBTL1ARACP1
SCHEMBL22985160 0.89 KIF11 (0.34) ARSCN9A
SCHEMBL22985475 0.89 KDM4E (0.30) KDM4EATML3MBTL1AR
SCHEMBL22985601 0.89 KDM4E (0.35) KDM4EATML3MBTL1ARACP1
SCHEMBL22985581 0.89 ELANE (0.34) ARSCN9AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 KDM4E 1604/4885ATM 2886/4885L3MBTL1 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.