SCHEMBL22986540

SCHEMBL22986540

CC(F)COC(=O)C(F)F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
TDP1 Q9NUW8 1/20 0.31
CTSA P10619 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27888652 0.84 TSHR (0.48) TSHRTDP1ALDH1A1
SCHEMBL17930160 0.84 TSHR (0.33) TSHRTDP1ALDH1A1
SCHEMBL609447 0.81 ALDH1A1 (0.41) TSHRTDP1ALDH1A1
SCHEMBL25953848 0.80 TSHR (0.31) TSHR
SCHEMBL8888899 0.79
SCHEMBL1817868 0.79
SCHEMBL9937119 0.78 TSHR (0.34) TSHRALDH1A1
SCHEMBL24481872 0.78 MAPT (0.31) TSHR
SCHEMBL4243979 0.78 NOTUM (0.30)
SCHEMBL13367959 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3780231-A1 ELECTROLYTE, ELECTROCHEMICAL DEVICE, LITHIUM-ION SECONDARY BATTERY, AND MODULE DAIKIN INDUSTRIES, LTD. (JP) 2021-02-17 EP disclosed