Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309170 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL16204287 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL18966397 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL20029373 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL18929799 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL21511141 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL20332659 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL14234461 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL21101608 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG | |
| SCHEMBL18251109 | 1.00 | CES2 (0.44) | CES2CES1HSP90AA1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777891-A1 | ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID | Institute of Basic Medical Sciences, Chinese Academi of Medical Sciences (CN) | 2021-02-17 | — | — | EP | disclosed |