Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987134 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1GAAPOLBCNR2 | |
| SCHEMBL19067551 | 0.71 | TTR (0.52) | HDAC1HDAC6KDM4EALDH1A1CA1 | |
| SCHEMBL22987140 | 0.71 | KDM4E (0.49) | KDM4EALDH1A1GAAPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL11643074 | 0.70 | HDAC1 (0.35) | HDAC1HDAC6KDM4EPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL11629282 | 0.70 | TTR (0.50) | HDAC1HDAC6KDM4EALDH1A1POLB | |
| SCHEMBL8048369 | 0.69 | HDAC1 (0.46) | HDAC1HDAC6POLBAPEX1 | |
| SCHEMBL24901830 | 0.69 | GAA (0.47) | HDAC1HDAC6KDM4EALDH1A1GAA | |
| SCHEMBL22987071 | 0.69 | ESR1 (0.40) | HDAC1HDAC6KDM4EALDH1A1GAA | |
| SCHEMBL11629278 | 0.68 | CA1 (0.47) | HDAC1HDAC6ALDH1A1CA1CA2 | |
| SCHEMBL23948541 | 0.68 | CA1 (0.47) | HDAC1HDAC6ALDH1A1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925848-B2 | Amide derivative | IDO1, IDO2, TPH1 | HDAC1 101/4885HDAC6 207/4885KDM4E 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.