SCHEMBL22987210

SCHEMBL22987210

CNCC(=O)N[C@@H](CCc1ccccc1)C(=O)NCCN1C(=O)C=CC1=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.55
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47
MMP8 P22894 7/20 0.45
GSK3A P49840 3/20 0.44
GSK3B P49841 3/20 0.44
MGLL Q99685 2/20 0.44
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
MMP1 P03956 2/20 0.41
MMP9 P14780 1/20 0.41
FAAH O00519 1/20 0.41
MMP2 P08253 1/20 0.41
MMP12 P39900 1/20 0.41
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22987290 0.89 AKT1 (0.69) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22987328 0.88 AKT1 (0.57) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22915443 0.86 AKT1 (0.68) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22915375 0.79 AKT1 (0.70) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22915402 0.79 AKT1 (0.70) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL23627513 0.78 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4MMP8
SCHEMBL22987323 0.78 AKT1 (0.66) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22987322 0.78 AKT1 (0.69) AKT1GSK3AGSK3BMGLLCTSS
SCHEMBL22915395 0.76 AKT1 (0.67) AKT1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22915441 0.76 AKT1 (0.83) AKT1CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778653-A1 NOVEL REACTIVE ALGINIC ACID DERIVATIVES Mochida Pharmaceutical Co., Ltd. (JP) 2021-02-17 EP disclosed